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What does the Avise panel test for?

What does the Avise panel test for?

AVISE® CTD is a blood test that can help doctors diagnose lupus and other autoimmune diseases — like rheumatoid arthritis, Sjögren’s syndrome, or scleroderma.

What is Avise lupus test?

The AVISE CTD test is an advanced diagnostic blood test for lupus and connective tissue diseases. AVISE CTD contains patented biomarkers and algorithms to provide improved diagnostic information compared to traditional lab tests alone.

What does a positive Avise test mean?

A positive Avise Lupus test result aids in formulating a SLE diagnosis when diagnosis based on standard-of-care tests and clinical features may be challenging, and impacts patient management. Prospective studies will be performed to better evaluate the clinical utility of the test and of CB-CAPs as biomarkers of SLE.

How do I test SLE activity?

SLE disease activity can be evaluated by assessing antibodies to double-stranded DNA (dsDNA), complement (C3, C4, and CH50), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) levels.

What is Avise SLE prognostic?

AVISE® SLE Prognostic is a 10-marker panel developed to help assess a patient’s potential risk for Thrombosis, Cardiovascular events, Lupus Nephritis and Neuropsychiatric Lupus.

How long is Avise test?

How long does it take to get results? AVISE CTD results are provided to the ordering physician within 5 business days from receipt of the sample.

Why is C3 and C4 low in SLE?

Lupus patients usually have low C3 and C4 levels during disease flares because of activation of the complement system by immune complexes (ICs) [1].

What is the SLE disease activity index?

Systemic lupus erythematosus disease activity index and its versions. The SLEDAI is a global index that was developed and introduced in 1985 as a clinical index for the assessment of lupus disease activity in the preceding 10 days. It consists of 24 weighted clinical and laboratory variables of nine organ systems.

What does Avise lupus result equivocal mean?

AVISE® Lupus Result : Negative – Index: -5.0. A result is marked as equivocal when one or more critical values is close to a threshold that would significantly change the index value if the threshold was crossed.

How long do Avise results take?

How accurate is Avise CTD test?

High levels of EC4d, B-cell-bound C4d (BC4d) and platelet-bound C4d (PC4d) can differentiate SLE from other CTDs with 56%–72% sensitivity and 80%–98% specificity, and from healthy individuals with 60%–81% sensitivity and 91%–100% specificity.

What blood tests confirm lupus?

Antibody blood tests The test you will hear about most is called the antinuclear antibodies test (the ANA test). 97% of people with lupus will test positive for ANA. ANA connect or bind to the nucleus or command center of the cell. This process damages and can destroy the cells.