Which pumps are used in supercritical fluid chromatography?
MX Class Pumps With pressure capability up to 5,000 psi, the MX Class can be used in both analytical and small-scale preparative HPLC separations.
Can you pump supercritical fluid?
Various types of pumps can be used for supercritical fluid applications. For medium to large volume processes, a pneumatic booster pump is most often used.
How does a supercritical fluid work?
When a gas such a carbon dioxide is compressed and heated, its physical properties change and it is referred to as a supercritical fluid. Under these conditions, it has the solvating power of a liquid and the diffusivity of a gas.
What is supercritical fluid system?
A supercritical fluid (SCF) is any substance at a temperature and pressure above its critical point, where distinct liquid and gas phases do not exist, but below the pressure required to compress it into a solid.
Which pump used in super critical fluid is determined by column type?
high pressure pump
In general type of high pressure pump used in super critical fluid is determined by column type. For packed columns for easier blending of mobile phase or introduction of modifier fluids reciprocating pumps are generally used.
Why SFC is better than HPLC?
SFC is theoretically up to ten times faster than HPLC,7 because of the lower viscosity and higher diffusivity in the mobile phase, SFC columns typically provide a three- to five-fold reduction in analysis time over HPLC.
Can supercritical CO2 be pumped?
In a supercritical state, the CO2 can be pumped like a liquid but has the effusiveness of a gas. This means that as it sweeps through the reservoir to push the oil to the riser, it is more effective than water, making for a more efficient process.
What is super critical pressure?
Supercritical fluid is a fluid at pressures and temperatures that are higher than its critical pressure and critical temperature. However, quite often in various publications, a term supercritical fluid includes both terms—supercritical fluid and compressed fluid.
What is the importance of supercritical fluids?
The use of most supercritical (SC) fluids in industrial processes can replace far more damaging conventional solvents. The most important SCFs, such as SC CO2 and SC H2O, are nontoxic, non-flammable, non-carcinogenic, non-mutagenic, and also thermodynamically stable.
What is the purpose of supercritical fluid extraction?
Supercritical fluid extraction (SFE) has been widely used for extracting flavor and fragrance compounds from complex matrices without the use of organic solvents. This method is based on the use of gases at determined conditions of pressure and temperature, known as supercritical region.
Why co2 is used in SFC?
Mobile Phases The most common supercritical fluid which is used in SFC is carbon dioxide because its critical temperature and pressure are easy to reach.
Which detector is used in SFC?
Developments in the following GC detectors as they have been used in SFC are reviewed: flame ionization detector (FID), thermionic ionization detector (TID), flame photometric detector (FPD), photoionization detector (PID), and electron capture detector (ECD).