Which kind of cell does Aschoff cell come from?
Aschoff believed that Aschoff giant cells were some type of connective or endothelial tissue. Today Aschoff cells are considered to be derived from cardiac myocytes rather than connective tissue cells.
Are Aschoff bodies macrophages?
Fully developed Aschoff bodies are granulomatous structures consisting of fibrinoid change, lymphocytic infiltration, occasional plasma cells, and characteristically abnormal macrophages surrounding necrotic centres. Some of these macrophages may fuse to form multinucleated giant cells.
What does Jones criteria stand for?
The revised Jones criteria are guidelines decided on by the American Heart Association to help doctors diagnose rheumatic fever. Two major criteria or one major and two minor criteria plus laboratory evidence of a preceding group A streptococcal (GAS) infection are required to make the diagnosis of rheumatic fever.
What are vegetations in rheumatic fever?
The rheumatic vegetations or verrucae arise due to inflammatory erosion of the valve surface, followed by platelet and fibrin precipitation. They are the cardinal feature of rheumatic endocarditis.
What is the name of the bacteria that causes acute rheumatic fever?
Rheumatic fever can occur after a throat infection from a bacteria called group A streptococcus. Group A streptococcus infections of the throat cause strep throat or, less commonly, scarlet fever.
What is vegetation in infective endocarditis?
The characteristic lesion seen with infective endocarditis, termed “the vegetation,” is composed of bacteria surrounded by a platelet/fibrin layer attached to the underlying endothelium.
What is mural endocardium?
(myū’răl en’dō-kahr-dī’tis) Inflammation of the endocardium involving the walls of the chambers of the heart.
What is the main difference between rheumatic heart disease RHD and acute rheumatic fever ARF )?
ARF is an illness that can affect the skin, joints, brain and heart. The skin, joints and brain recover from ARF, but the heart can suffer lasting damage. The lasting heart damage that remains after an episode of ARF is called rheumatic heart disease (RHD).
What is the difference between scarlet fever and rheumatic fever?
Scarlet fever is an illness that is caused by a bacterial infection. Rheumatic fever is an inflammatory condition that can develop if scarlet fever is not identified and treated early. Scarlet fever, if untreated, may develop into rheumatic fever.