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What is the difference between MDA-MB-231 and MDA-MB-468?

What is the difference between MDA-MB-231 and MDA-MB-468?

MDA-MB-468 is a basal BC cell line while MDA-MB-231 is a claudin-low cell line – a point Hamed Helal made above, to his credit – with claudin-3, claudinin-4 and claudinin-7 low, and typically with low Ki67 and E-cadherin, in contrast to MDA-MB-468 absent these and itself with high Ki-67 and as I noted, MDA-MB-231 shows …

What does MDA-MB-231 mean?

Abbreviation / Long Form : MDA-MB 231 / M.D. Anderson – Metastatic Breast 231.

What are t47d cells?

T-47D are epithelial cells isolated from a pleural effusion obtained from a 54-year-old female patient with an infiltrating ductal carcinoma of the breast. Use these cells in your breast cancer research. Homo sapiens, human.

What are bt474 cells?

BT-474 is a cell line exhibiting epithelial morphology that was isolated from a solid, invasive ductal carcinoma of the breast obtained from a 60-year-old, White, female breast cancer patient. Use these cells in your cancer research.

Do MDA-MB-231 cells express HER2?

MDA-MB-231 is a highly aggressive, invasive and poorly differentiated triple-negative breast cancer (TNBC) cell line as it lacks oestrogen receptor (ER) and progesterone receptor (PR) expression, as well as HER2 (human epidermal growth factor receptor 2) amplification2,3.

What is MDA-MB-468 cell line?

MDA-MB-468 is a cell line with epithelial morphology that was isolated from a pleural effusion of a 51-year-old Black female patient with metastatic adenocarcinoma of the breast. These cells have applications in breast cancer and immuno-oncology research.

How long does it take MDA-MB-231 cells to adhere?

5-7 days
Just aspirate the media and add more. After this, you should see some cells happily attached. Do not change the media or split cells before they are about 60% confluent (which can take 5-7 days for MDA-MB-231, depending on how many survive thawing), unless there are a lot of dead cells floating.

What is the doubling time for MDA-MB-231?

The doubling times for exponentially growing MDA-MB-231 cells were 28.9 h, whereas the doubling times of the eight microcell hybrids varied between 33.4 h (CT60/4) and 44.6 h (CT60/8) (medium 37.7 h) (Figure 2a).

What is mcf7 cell line?

1 MCF-7 human adenocarcinoma cells. MCF-7 is a human breast cancer cell line with estrogen, progesterone and glucocorticoid receptors [26]. It is derived from the pleural effusion of a 69-year-old Caucasian metastatic breast cancer (adenocarcinoma) in 1970 by Dr Soule of the Michigan Cancer Foundation, Detroit, MI [27] …

What is MCF 10A?

MCF 10A is an epithelial cell line that was isolated in 1984 from the mammary gland of a White, 36-year-old female with fibrocystic breasts. This cell line was deposited by the Michigan Cancer Foundation. Homo sapiens, human. Cell type epithelial cell Morphology epithelial Tissue Breast; Mammary gland Disease.

What are skbr3 cells?

SK-BR-3 is a human breast cancer cell line that overexpresses the Her2 (Neu/ErbB-2) gene product. These cells display an epithelial morphology in tissue culture and are capable of forming poorly differentiated tumors in immunocompromised mice.

What is A549 cell line?

A549 cells are lung carcinoma epithelial cells that constitute a cell line. A549 is one of the commonly used cell lines for a wide range of research applications.