What is Ruconest used for?
This medication is used to treat the swelling problems caused by a certain immune disease passed down through families (hereditary angioedema-HAE). HAE is caused by low levels or improper function of a natural substance produced by the body (C1-esterase inhibitor).
How often can you take ruconest?
Be sure not to take more than two doses of Ruconest in 24 hours.
How much does Ruconest cost?
The cost for Ruconest intravenous powder for injection 2100 intl units is around $7,233 for a supply of 1 powder for injection, depending on the pharmacy you visit.
How is Ruconest administered?
RUCONEST will be dissolved in sterile water and slowly injected into your vein (intravenous injection). The most common side effects patients experienced during clinical studies include headache, nausea and diarrhea.
How long does ruconest last?
After mixing Ruconest, store in the refrigerator and use within 8 hours. Do not freeze. Mixed medicine should be used right away if you keep it at room temperature. c1 esterase inhibitor doses are based on weight.
How do you know if you have angioedema?
The main symptom is sudden swelling below the skin surface. Welts or swelling on the surface of the skin can also develop. The swelling usually occurs around the eyes and lips. It may also be found on the hands, feet, and throat.
Who manufactures ruconest?
Manufacturer: Salix Pharmaceuticals, Inc.
Is there a cure for hereditary angioedema?
Hereditary angioedema cannot be cured, but medicines can help prevent and treat the swelling.
What triggers angioedema?
Angioedema can be triggered by an allergic reaction to: certain types of food – particularly nuts, shellfish, milk and eggs. some types of medicine – including some antibiotics, aspirin and non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen. insect bites and stings – particularly wasp and bee stings.
What is the treatment for hereditary angioedema?
Treatment of Hereditary Angioedema: Replacement therapy or immune modulating medicines pertaining to hereditary angioedema. Intravenous medication to treat acute attacks of hereditary angioedema. To prevent angioedema due to C1 esterase inhibitor deficiency.
What are the uses of conestat alfa?
Conestat alfa is used to treat angioedema attacks in people with hereditary angioedema. Conestat alfa is for use in adults and children who are at least 13 years old. Conestat alfa may also be used for purposes not listed in this medication guide. What should I discuss with my healthcare provider before using conestat alfa?
What is the recommended dose of conestat alfa for an acute attack?
The recommended dose of conestat alfa for an acute HAE attack is 50 IU/kg for patients weighing less than 84 kg up to 4,200 IU for patients weighing 84 kg or more, to be administered as a slow intravenous injection over five minutes.
What is the molecular mass of conestat alfa?
Conestat alfa is a soluble, single-chain glycoprotein containing 478 amino acids with a molecular mass of 68 (kDa), of which approximately 22% comprises oligosaccharide structures.
How long does it take for conestat alfa to work?
Among U.S. patients, the median time to the beginning of relief of symptoms with persistence at the primary attack location was 98 minutes in patients treated with conestat alfa [95% CI, 45–240, n = 22] compared with 90 minutes in patients treated with placebo [95% CI, 50–NE, n = 16].