What is Carbopol 971?
Carbopol® 971P NF polymer is used in oral and mucosal contact applications such as extended/controlled release tablets, oral liquids and suspension and bioadhesive formulations. It is a lightly crosslinked polymer with long rheology, which will result in flow like honey in a semisolid formulation.
What is the difference between Carbomer and Carbopol?
Carbopol 934 is cross-linked with allyl sucrose and polymerized in benzene. Carbopol 71, 971, and 974 are cross-linked with allylpentaerythritol and polymerized in ethyl acetate. Carbomer polymers contain 56%–68% of carboxylic acid (–COOH) groups and 0.75%–2% of cross-linking agents.
What is Carbopol used for?
Carbopol® (Carbomer) In the cosmetic industry, Carbopol is used as a thickener in lotions, creams and gels. It is also used to stabilize, suspend, and control the release of pharmaceutical products. At low concentrations, suspensions flow easily with a slippery feel.
What is the category of Carbopol 980 NF?
Carbomer Homopolymer Type C USP NF.
What is the difference between Carbopol 940 and 980?
The key difference between carbomer 940 and 980 is that carbomer 940 is important as a rheological modifier, while carbomer 980 is important as a thickening agent. Carbomer is the market name of polyacrylate polymer. There are different types of carbomer materials based on their composition and applications.
How do you make Carbopol gel?
Preparation of Glibenclamide gel The 100 g gel was prepared by direct dispersion method. In this firstly, propyl paraben was dissolved in water at 80ºC and then accurately weighed quantity of carbopol 940 was dispersed in water at 40ºC with constant stirring for 30 min [8].
Is Carbopol safe for skin?
“Carbomer has been assessed as safe to use in cosmetic products,” he assures. “It has been shown that carbomers can be used by everyone and have no adverse effect.” Known to be safe for all skin types, carbomers are fluffy white powders that allow other ingredients in your products to work together to get the job done.
What is the difference between Carbomer 940 and 980?
What is Carbomer 980 used for?
Carbopol® 980 polymer It is an extremely efficient rheology modifier capable of providing high viscosity and forms sparkling clear gels or hydro-alcoholic gels and creams. Its short flow, non-drip properties are ideal for applications such as clear gels, hydroalcholic gels, creams, and lotions.
How do you dissolve Carbopol in water?
Using moderate to vigorous agitation (800-1200 rpm), add the oil phase containing Carbopol® polymer to the water phase. The water phase should contain an appropriate neutralizing base. Continue to mix for 15-20 minutes until the Carbopol® polymer has swelled to produce a smooth emulsion.
Is Carbopol natural?
Carbopol 940, also known as Carbomer, is a 100% synthetic thickening agent derived from acrylic acid and is so distantly removed from most natural chemical compounds that it simply doesn’t cause negative reactions on the skin.
Is there any toxicology data available for carbopol 974p NF polymer?
Lubrizol has supporting data for dermal, ocular, and oral toxicology testing for Carbopol 974P NF polymer. Bulletin 2 provides a summary of all toxicology studies for Lubrizol’s pharmaceutical grade polymers. Additionally, Lubrizol has filed a Type V DMF with FDA.
Does Lubrizol have a type V DMF?
Bulletin 2 provides a summary of all toxicology studies for Lubrizol’s pharmaceutical grade polymers. Additionally, Lubrizol has filed a Type V DMF with FDA. A letter of authorization (LOA) can be issued for FDA drug applications.
Is Lubrizol approved by the FDA?
Additionally, Lubrizol has filed a Type V DMF with FDA. A letter of authorization (LOA) can be issued for FDA drug applications.
Can carbopol polymers be combined with powder grades polymers?
Powder and granular grade Carbopol polymers can be combined in a formulation to achieve desired release profiles. The release rates can be modulated by incorporating powder grades polymers, such as Carbopol 971P NF or 974P NF, and then blending with Carbopol 71G NF granular polymer.