What can cause high triglycerides in dogs?
Causes of high triglycerides in dogs Medical conditions, such as diabetes, pancreatitis, hypothyroidism, some kidney conditions, and Cushing’s disease can lead to hyperlipidemia. Nephrotic syndrome, a condition that causes a dog’s liver to produce too much cholesterol, can also result in hyperlipidemia.
How is familial hypertriglyceridemia treated?
The initial treatment should be lifestyle therapy; a combination of diet modification and drug therapy may also be considered. In patients with severe or very severe hypertriglyceridemia, a fibrate should be used as a first-line agent.
What genetic conditions cause high triglycerides?
Familial hypertriglyceridemia is a genetic condition that causes the triglyceride levels in the blood to get too high. This relatively common condition affects about 1 in 500 people in the United States. Familial hypertriglyceridemia is typically inherited in a dominant manner.
What are the most common causes of hypertriglyceridemia?
Obesity is probably the metabolic stressor most frequently associated with hypertriglyceridemia, although associations with poorly controlled type 2 diabetes and excessive alcohol consumption are also common. Obesity, metabolic syndrome, diabetes.
What to feed dogs with high triglycerides?
The 8 Best Dog Foods for High Triglycerides
- Wellness CORE Reduced Fat Dry Dog Food – Best Overall.
- Rachael Ray Nutrish Zero Grain Dry Dog Food – Best Value.
- The Honest Kitchen Dehydrated Dog Food – Best for Puppies.
- Merrick Grain-Free Healthy Weight Recipe Dry Dog Food.
How is familial hypertriglyceridemia diagnosed?
If you have a family history of this condition, you should have blood tests to check very low density lipoprotein (VLDL) and triglyceride levels. Blood tests most often show a mild to moderate increase in triglycerides (about 200 to 500 mg/dL). A coronary risk profile may also be done.
What is the first line treatment for hypertriglyceridemia?
Fibrates are the first-line treatment in patients with hypertriglyceridemia who are at risk of pancreatitis. Fibrates, niacin, and n-3 fatty acids, alone or in combination, should be considered in patients with moderate to severe hypertriglyceridemia.
What is familial combined hyperlipidemia?
Familial combined hyperlipidemia is a disorder that is passed down through families. It causes high cholesterol and high blood triglycerides.
Is hypertriglyceridemia serious?
Individuals with severe hypertriglyceridemia (SHTG) have triglyceride levels more than three times the normal level. SHTG can lead to multiple serious conditions, including cardiovascular disease (CVD) and acute pancreatitis.
What happens in hypertriglyceridemia?
High triglyceride levels cause arterial blockage, which can lead to coronary heart disease, stroke, and peripheral arterial disease. Pancreatitis can also occur if the triglyceride levels are very high. Other complications of hypertriglyceridemia include obesity and diabetes.
What is Familial hypertriglyceridemia?
Familial hypertriglyceridemia (type IV familial dyslipidemia) is a disorder characterized by the overproduction of very low-density lipoproteins (VLDL) from the liver. As a result, the patient will have an excessive number of triglycerides and VLDL on the lipid profile.
Are Statins safe for dogs with hypertriglyceridemia?
Because of these potential side effects in dogs and cats and the lack of convincing efficacy in lowering triglyceride concentration, we rarely use statins to treat hypertriglyceridemia. Treatment of hypercholesterolemia relies largely on diet and occasionally on pharmacologic intervention.
What is pathological hyperlipidemia in dogs?
Pathological hyperlipidemia can result from increased lipoprotein synthesis or mobilization or decreased lipoprotein clearance.1 It can be primary (genetic or idiopathic) or secondary to other disease processes.1 Veterinarians should be familiar with how to recognize and manage this clinical disorder.
What factors affect the expression of hypertriglyceridemia in heterozygous familial lipoprotein lipase deficiency?
Hyperinsulinemia and abdominal obesity affect the expression of hypertriglyceridemia in heterozygous familial lipoprotein lipase deficiency. [Diabetes. 1997]
https://www.youtube.com/watch?v=okNAPc9wz38