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What are the symptoms of CREST disease?

What are the symptoms of CREST disease?

CREST Syndrome and Scleroderma

  • Calcinosis — Painful lumps of calcium in the skin.
  • Raynaud’s phenomenon — White or cold skin on the hands and feet when you’re cold or stressed.
  • Esophageal dysfunction — Problems swallowing and/or reflux.
  • Sclerodactyly – Tightness and thickening of finger or toe skin.

How long can you live with CREST syndrome?

In a large 2003 US study by Mayes et al, the survival rate from time of diagnosis was computed to be 77.9% at 5 years, 55.1% at 10 years, 37.4% at 15 years, and 26.8% at 20 years. The extent of skin involvement is a good predictor of survival in patients with scleroderma.

What causes CREST syndrome?

Exposure to silica, synthetic adhesives, solvents (including chlorinated solvents, aromatic solvents, white spirit, toluene, trichloroethylene, formaldehyde, vinyl chloride, and cleaning products) have been implicated in a higher risk of developing systemic sclerosis.

Is CREST syndrome an autoimmune disease?

CREST is a type of collagen vascular disease. It is believed to be an autoimmune condition. CREST is a type of scleroderma. There are two types of scleroderma — localized and systemic — and CREST is considered a mild form of systemic scleroderma.

What is the best treatment for CREST syndrome?

Simple surgical management, including curettage, is often sufficient in limited disease. Treatment with oral corticosteroids is not usually considered effective, but, according to Hazen et al, intralesional corticosteroid therapy has been associated with improvement of calcinosis.

Can you get disability for CREST syndrome?

If you suffer from CREST syndrome and are no longer able to work because of the effects of your symptoms on your daily functioning, you may be eligible to receive Social Security disability benefits, either through SSDI or SSI.

Does CREST syndrome cause pain?

What Are Signs and Symptoms of CREST Syndrome? Calcium deposits can be tender and painful. Deposits may become ulcerated, have a white chalky substance drain from them, and secondary infection can occur. There may be inflammation at the site of the calcinosis.

Does CREST syndrome cause fatigue?

You may also feel very tired. Some people describe this tiredness as similar to that in people getting cancer treatment. Or it’s similar to the fatigue caused by lupus or rheumatoid arthritis. Over time, CREST syndrome can cause problems with your internal organs, such as your heart and lungs.

Can CREST syndrome be cured?

Scleroderma is treatable, resulting in a long and excellent quality of life. The exact management plan must be customized to meet the individual patient’s needs. Scleroderma can be severe with systemic organ disease and treatment needs to start early to prevent complications.

What were your first symptoms of scleroderma?

Early symptoms may include swelling and itchiness. Affected skin can become lighter or darker in color and may look shiny because of the tightness. Some people also experience small red spots, called telangiectasia, on their hands and face.

Where does scleroderma usually start?

Another early sign of systemic scleroderma is puffy or swollen hands before thickening and hardening of the skin due to fibrosis. Skin thickening usually occurs first in the fingers (called sclerodactyly) and may also involve the hands and face.

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