Is there a cure for Elephant Man syndrome?
There is no cure for neurofibromatosis, also known as the Elephant Man’s Disease, so named after John Merrick, a victim who lived in the 19th century and was known as the Elephant Man. Mr. Merrick had the disease on most of his body; Lisa’s is almost totally confined to her face.
What causes neurofibromatosis?
Causes. NF1 is caused by mutations in the gene that controls production of a protein called neurofibromin (neurofibromin 1). This gene is believed to function as a tumor suppressor. In about 50% of people with NF1, the disorder results from gene mutations that occur for unknown reasons (spontaneous mutation).
What caused the Elephant Man’s deformity?
As he grew, a noticeable difference between the size of his left and right arms appeared and both his feet became significantly enlarged. The Merrick family explained his symptoms as the result of Mary’s being knocked over and frightened by a fairground elephant while she was pregnant with Joseph.
What is the life expectancy of a person with Proteus syndrome?
Life expectancy is 9 months to 29 years, according to “Radiologic manifestations of Proteus syndrome” published in the Radiological Society of North America journal RadioGraphics.
Where can you get elephantiasis?
It’s caused by parasitic worms, and can spread from person to person through mosquitoes. Elephantiasis causes swelling of the scrotum, legs, or breasts. Elephantiasis is considered a neglected tropical disease (NTD). It’s more common in tropical and subtropical areas of the world, including Africa and Southeast Asia.
Can neurofibromatosis be removed?
Neurofibroma Surgery Your doctor may recommend surgical removal of a neurofibroma that is causing pain or weakness, that is growing fast or that is suspected of developing into cancer. Depending on the tumor’s location and size and its involvement with the underlying nerve, neurofibroma surgery can be complicated.
Can Proteus syndrome be cured?
Most people with Proteus syndrome have a variant seen in the AKT1 gene in some, but not all cells of the body. There is no cure or specific treatment for Proteus syndrome and treatment involves medical and surgical management of symptoms.
Is Proteus syndrome painful?
Individuals with Proteus syndrome may be at risk for developing blood clots in the legs a condition known as deep vein thrombosis (DVT). The legs may become painful and swollen and blood vessels in the legs may be visibly enlarged.
How is elephantiasis diagnosed?
Your doctor can find out if you have elephantiasis by giving you a physical exam. They will ask about your medical history, and whether you’ve traveled to a place where you were more likely to have gotten elephantiasis. They also will have blood tests done to see if roundworms are in your bloodstream.