Is sodium edetate the same as EDTA?
Sodium calcium edetate (sodium calcium EDTA), also known as edetate calcium disodium among other names, is a medication primarily used to treat lead poisoning, including both short-term and long-term lead poisoning.
What is the formula of disodium EDTA?
EDTA (Disodium) | |
---|---|
Chemical Formula | [(HO2CCH2-)(NaO2CCH2-)N-CH2]2·2H2O |
Formula Weight | 372.24 |
Equivalent Weight | 186.12 (Molar = 2 Normal)* |
CAS No. | 6381-92-6 |
What is Na2EDTA?
Na2EDTA is EDTA, disodium salt dihydrate. Since it has two molecules of water, it should be easier to dissolve in water than anhydrous form.
What is the name of Na2EDTA?
Ethylenediaminetetraacetic Acid, Disodium Salt (Na2-EDTA)
What is disodium edetate in eye drops?
Edetate disodium is used to bind chemicals called proteinases and metalloproteinases that break down the clear part of the eye (cornea) and to remove calcium deposits in the eye.
What is EDTA in mayonnaise?
What Is EDTA? Ethylenediamine tetraacetic acid (EDTA) is one of the most commonly used food preservatives worldwide. It’s also known as edetate calcium disodium or EDTA calcium disodium. Food manufacturers add it to mayo, salad dressings, spreads and canned legumes to preserve their color and flavor.
What is the difference between EDTA and disodium EDTA?
They are sodium salts of EDTA. Disodium EDTA has two sodium cations whereas tetrasodium EDTA has four sodium cations per molecule. The main difference between disodium EDTA and tetrasodium EDTA is that disodium EDTA has a pH lower than 7 whereas tetrasodium EDTA has a pH higher than 7.
What is disodium EDTA used for?
EDETATE DISODIUM, EDTA (ED uh teyt di SOE dee um) EDTA binds with calcium and some heavy metals in the body. It is used to treat calcium overload. It is also used to treat irregular heart beats caused by too much digitalis (digoxin or digitoxin).
How do you make Na2EDTA?
To prepare EDTA at 0.5 M (pH 8.0): Add 186.1 g of disodium EDTA•2H2O to 800 mL of H2O. Stir vigorously on a magnetic stirrer. Adjust the pH to 8.0 with NaOH (~20 g of NaOH pellets). Dispense into aliquots and sterilize by autoclaving.
Why is Na2EDTA used?
Na2EDTA (Ethylene diamine tetraacetic acid disodium salt or in short Sodium EDTA) easily binds with calcium. It is used intravenously in the treatment of hypercalcemia and of atherosclerotic disease.
What is EDTA anticoagulant?
Ethylenediaminetetraacetic acid (EDTA) is a well-known anticoagulant since early 1950s and it has certain advantages over other anticoagulants [2]. It inhibits clotting by removing or chelating calcium from the blood.
Is EDTA safe for eye drops?
Conclusions: These data show that the new preservative NIG/EDTA, at doses known to have effective antimicrobial properties, has a very low toxicity on corneal cells, and so it can be safely used in multi-dose eye drops.
What is the molecular weight of sodium edetate?
Sodium edetate Common Name Sodium edetate Sodium edetate Sodium edetate CAS Number 64-02-8 Molecular Weight 380.170 Density 6.9 g/cm3 Boiling Point 614.2ºC at 760 mmHg Molecular Formula C 10 H 12 N 2 Na 4 O 8 Melting Point >300 °C (lit.) MSDS Chinese Flash Point 325.2ºC
What is the chemical formula for sodium acetate?
The sodium acetate chemical formula or sodium ethanoate formula is explained below. Sodium acetate is a sodium salt of ethanoic acid (acetic acid) and contains two carbon atoms, 3 hydrogen atoms, 1 sodium atom, and 2 oxygen atoms.
What are the different salts of EDTA?
A number of salts of EDTA are available with uses identical or similar to the acid. The USP salts are called edetates ( calcium disodium, disodium edetates); others are usually abbreviated to EDTA ( tetrasodium, trisodium EDTA ).
Are edetic acid and na4edta toxic?
Both edetic acid and Na4EDTA are mild skin irritants, but comparatively potent eye irritants. European Commission; Scientific committee on Toxicity, Ecotoxicity and the Environment; Opinion on the results of the Risk Assessment of: Tetrasodium Ethylenediamine Tetraacetate (64-02-8) and Edetic Acid (60-00-4) Human Health Part (September 2003).