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Does alcohol affect thalassemia?

Does alcohol affect thalassemia?

Patients with thalassaemia should be discouraged from consuming alcohol, as it can facilitate the oxidative damage of iron and aggravates the effect of HBV and HCV on liver tissue.

How does beta thalassemia trait affect pregnancy?

Pregnant women with beta thalassemia can develop anemia, which can raise the chances of delivering early. You also may need more frequent blood transfusions during pregnancy for your health and the health of your baby.

Can thalassemia patient have normal baby?

Children with thalassemia are usually normal at birth but soon develop symptoms including fatigue, shortness of breath, jaundice, and enlargement of the spleen. If you have thalassemia and your partner carries the trait for thalassemia, there is a chance that your baby may inherit the disease.

What is the most common cause of beta thalassemia major?

Most beta thalassemia cases are caused by a mutation in the HBB gene. In extremely rare cases, a loss of genetic material (deletion) that includes the HBB gene causes the disorder. Genes provide instructions for creating proteins that play a critical role in many body functions.

What should thalassemia patients avoid?

Thalassemia patients should avoid pork, liver, oysters, beans, beef, peanut butter and tofu from their diet. They should also avoid consumption of prunes and prune juice, watermelon, spinach, leafy green veggies, dates, broccoli, raisins and peas.

Is beta thalassemia minor a disability?

With regard to medical eligibility, the SSA considers beta thalassemia an inherently disabling disease.

Can you test fetus for thalassemia?

If your baby is at risk for thalassemia, you can have prenatal tests during pregnancy to see if he has the condition. Prenatal tests are tests you get during pregnancy to see how you and your baby are doing. Talk to your health care provider about these tests: Chorionic villus sampling (also called CVS).

How long do minor thalassemia patients live?

“Most thalassaemia patients would live up to the age of 25 to 30 years. Improved facilities will help them live up to the age of 60,” said Dr Mamata Manglani, head of pediatrics, Sion hospital.

Can I marry someone with thalassemia?

Thalassemia, related to the reduction in red blood cells, is rapidly increasing in India forcing doctors to make a fervent appeal for improved awareness and preventive measures at primary and social levels. No two Thalassemia minor patients should be allowed to marry.

Why is B thalassemia major usually evident only after birth?

This condition is called thalassemia major, or Cooley anemia. Babies born with two mutated beta hemoglobin genes are usually healthy at birth but disease starts to manifest after 6 months of life when fetal hemoglobin (Hb-gamma) disappears and is replaced by adult Hb.

Can beta thalassemia minor turn to major?

One mutated gene, you’ll have mild signs and symptoms. This condition is called thalassemia minor or beta-thalassemia. Two mutated genes, your signs and symptoms will be moderate to severe. This condition is called thalassemia major, or Cooley anemia.

What foods are not good for beta thalassemia minor?

Fruits/Vegetables that should be avoided or eliminated from the diet:

  • prune juice.
  • prunes.
  • watermelon.
  • spinach.
  • leafy green vegetables.
  • dates.
  • raisins.
  • broccoli.

What is beta-thalassemia (beta thalassemia)?

Beta-thalassemia is an inherited disease with a wide phenotypic severity of the disease. Manifestations of the disease occur in the form of chronic anemia as well as significant pathology associated with bone marrow expansion and extramedullary hematopoiesis.

What are the nutritional sequelae of thalassemia?

Other nutritional sequelae of thalassemia include relative folate deficiency, calcium depletion, and vitamin C deficiency.[7] Symptomatic hypersplenism is common in thalassemia intermedia and major and may be treated with splenectomy.

What are the chances of having a child with thalassemia minor?

If both parents have beta-thalassemia minor, there is a one-fourth chance that a child has thalassemia major. Careful genetic counseling is needed when one parent has thalassemia minor and the other parent has other beta globin-related diseases, such as sickle cell carriage.

What is the pathophysiology of thalassemia?

Thalassemias are a common cause of hypochromic microcytic anemia which arises from the reduced or absent synthesis of the globin chain of hemoglobin. Thalassemias are a quantitative defect of hemoglobin synthesis.