Are juvenile polyps premalignant?
Juvenile polyposis–a precancerous condition.
What is a premalignant polyp?
A polyp is a general term used for any growth that might be benign. A precancerous polyp by itself is not malignant but if left untreated can become cancerous. It is very common for adults to have polyps in their colon. Precancerous lesions can usually be surgically extracted to avoid cancer.
Are hamartomatous polyp cancerous?
A hamartoma is a growth of normal-appearing tissue that builds up into a benign (noncancerous) tumor. In PJS, hamartomatous polyps often develop in the small and large intestine, and they can cause bleeding or other problems, such as an intestinal blockage.
What are juvenile retention polyps?
Juvenile polyps, also known as retention or hyperplastic polyps, are typically benign colonic tumors diagnosed most commonly in children aged 2 to 10 years who present with painless hematochezia (see Chapter 122). The polyps are usually pedunculated, solitary, and located in the rectosigmoid colon.
Is Peutz Jeghers syndrome premalignant?
The polyps are not premalignant, but a definite association exists between Peutz-Jeghers syndrome and gastrointestinal carcinoma. Evidence shows that the syndrome is associated with an increased risk of extraintestinal malignancy, especially carcinomas of the pancreas, breast, and reproductive organs.
What is Peutz Jeghers syndrome?
Peutz Jeghers syndrome is part of a heterogeneous group of disorders, known as hamartomatous polyposis syndromes that involve the growth of multiple polyps in the gastrointestinal tract of affected individuals. It was first described in a pair of twin sisters with dark pigment spots on their lips and oral mucosa by Dr.
What causes precancerous polyps?
Mutations in certain genes can cause cells to continue dividing even when new cells aren’t needed. In the colon and rectum, this unregulated growth can cause polyps to form. Polyps can develop anywhere in your large intestine.
Is a precancerous polyp serious?
These types of polyps are not cancer, but they are pre-cancerous (meaning that they can turn into cancers). Someone who has had one of these types of polyps has an increased risk of later developing cancer of the colon. Most patients with these polyps, however, never develop colon cancer.
What is a hamartomatous polyp?
Hamartomatous polyps (HPs) in the gastrointestinal (GI) tract are rare compared to other types of GI polyps, yet they are the most common type of polyp in children. The symptoms are usually rectal bleeding, abdominal pain, obstipation, anaemia, and/or small bowel obstruction.
Is Peutz-Jeghers syndrome premalignant?
What type of polyp is a juvenile polyp?
Juvenile polyps are a type of polyp found in the colon. While juvenile polyps are typically found in children, they may be found in people of any age. Juvenile polyps are a type of hamartomatous polyps, which consist of a disorganized mass of tissue. They occur in about two percent of children.
Are juvenile polyps benign?
The polyps associated with juvenile polyposis syndrome are most often benign; however, they can change into a malignant cancer. A careful and detailed review of an individual’s medical and family history is important in diagnosing juvenile polyposis syndrome.