What is ulerythema ophryogenes?
Ulerythema ophryogenes, a rare cutaneous disorder, is characterized by inflammatory keratotic facial papules that may result in scars, atrophy, and alopecia. This disorder has been described in association with other congenital anomalies such as Noonan syndrome, de Lange syndrome, and Rubinstein-Taybi syndrome.
What is keratosis pilaris Atrophicans?
Keratosis pilaris atrophicans is a group of related disorders characterized by inflammatory keratotic papules that may result in alopecia and scarring. They include keratosis pilaris atrophicans faciei (also called ulerythema ophryogenes), atrophoderma vermiculatum, and keratosis follicularis spinulosa decalvans [1].
What genetic diseases are associated with keratosis pilaris?
KP is more common in patients affected by atopic diseases such as allergic rhinitis and atopic dermatitis. KP subtypes are occasionally part of genetically inherited syndromes associated with intellectual disability, neuro-cardio-facial-cutaneous syndromes, RASopathies, ectodermal dysplasias, and certain myopathies.
How is ulerythema ophryogenes treated?
Treatment for ulerythema ophryogenes has been unsatisfactory. Although local applications of salicylic acid, resorcinol, and the mercurials have been advocated, few, if any, cases respond. Recently, a patient was treated with hydrocortisone ointment with spectacular results.
What causes keratosis pilaris rubra Faceii?
What causes keratosis pilaris atrophicans faciei? Keratosis pilaris atrophicans faciei is caused by abnormal keratinisation of the follicular infundibulum. Scale fills the follicle and obstructs the hair shaft resulting in inflammation. Over time, chronic inflammation results in atrophy and alopecia [1].
How would you describe keratosis pilaris on a physical exam?
Physical findings of keratosis pilaris (KP) are limited to the skin. Upon gross examination, the skin of the outer-upper arms and thighs is frequently affected. The skin is described as chicken skin or goose-bumps. Often, 10-100 very small, slightly rough bumps are scattered in an area.
Is keratosis pilaris the same as strawberry legs?
Keratosis pilaris is most common in people with dry skin or eczema, says Dr. Reid, and is caused by excess keratin building up in your hair follicles. Usually, most people with lifelong “strawberry legs” are actually just dealing with keratosis pilaris—which, annoyingly, is genetic.
Is KP an autoimmune disease?
Keratosis pilaris is a common disorder in which dead cells shed from the upper layer of skin plug the openings of hair follicles. are more likely to have keratosis pilaris. However, keratosis pilaris does not seem to be a hypersensitivity or immune system disorder.
What autoimmune disease causes overproduction of keratin?
Scleroderma is a chronic but rare autoimmune disease in which normal tissue is replaced with thick tissue with extra collagen. Although it most often affects the skin, scleroderma also can affect many other parts of the body.
Can keratosis pilaris cause hair loss?
Keratosis pilaris atrophicans is a rare variant of keratosis pilaris, which is characterized by hair loss and follicular depressions that look like scars.
How do you get rid of keratosis pilaris on eyebrows?
Treatment with topical keratolytic agents, such as lactic acid, glycolic acid, salicylic acid, tretinoin, vitamin D3 analogue, or urea in combination with a topical corticosteroid or oral retinoids, has been used with some success.