What is the medication cisapride used for?
Cisapride is used to treat symptoms of nighttime heartburn in people who have not responded to other treatments.
Why was cisapride removed from the market?
Janssen Pharmaceutica, in consultation with the FDA, has decided to stop marketing the prokinetic agent cisapride (Propulsid®) on July 14, 2000 due to the risk of serious cardiac arrhythmias and death associated with this agent.
What are the side effects of cisapride?
Side effects are uncommon but vomiting, diarrhea, or gastrointestinal discomfort may occur. More serious side effects include incoordination, excessive drooling, muscle twitches, agitation, abnormal behavior, increased body temperature, and seizures; these signs may indicate doses are too high.
What kind of drug is cisapride?
What is this medicine? CISAPRIDE (SIS a pride) is used to treat heartburn in patients with gastroesophageal reflux disease (GERD). Because of the serious risks associated with this medicine it should only be used when lifestyle changes and other medicines have not worked.
When do you take cisapride?
Cisapride is used in cats to manage chronic constipation and megacolon. Work in humans has shown that cisapride is better absorbed when given with food. In small-animal practice it usually is recommended that cisapride be given orally 15 minutes before feeding.
When do you give cisapride?
Cisapride is usually given at least 30 minutes before feeding. Cisapride does not cure the condition for which it is given. Treatment is generally continued for the life of the animal.
What can I use instead of Cisapride?
Many currently available medications have equivalent or greater efficacy than cisapride for indications such as gastro-oesophageal reflux disease, functional dyspepsia, oesophageal dysmotility and constipation. The alternatives include acid suppressing drugs, domperidone, metoclopramide and laxatives.
When do you give Cisapride?
How long is cisapride good for?
Conclusions: Cisapride was stable in a suspension for 91 days at 4 degrees C and 28 days at 25 degrees C in amber plastic prescription bottles.
Is cisapride a human medication?
Cisapride is indicated for the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
Is cisapride a laxative?
Cisapride is used to stimulate motility for treating gastric reflux, gastroparesis, ileus, and constipation. The most common uses in animals have been to prevent stomach regurgitation, decrease postoperative ileus, and treat constipation and megacolon in cats.
How long does it take for cisapride to start working?
Cisapride is pretty fast acting, usually given about 15 minutes prior to eating. It speeds up motility in the digestive tract, it’s meant to help move the entire process along, not just constipation. To help avoid this in the future, you can add Miralax to the food.