What is proliferative glomerular disease?
Proliferative glomerulonephritis describes the finding of increased cellularity of the glomerulus, which may be due to proliferation of intrinsic glomerular cells, infiltration of leucocytes, or both.
What is meant by diffuse glomerulonephritis?
diffuse glomerulonephritis a severe form of glomerulonephritis with proliferative changes in more than half the glomeruli, frequently with epithelial crescent formation and necrosis; it is often seen in cases of advanced systemic lupus erythematosus.
What causes proliferative glomerulonephritis?
Acute proliferative glomerulonephritis (post-streptococcal glomerulonephritis) is caused by an infection with streptococcus bacteria, usually three weeks after infection, usually of the pharynx or the skin, given the time required to raise antibodies and complement proteins.
What causes diffuse proliferative glomerulonephritis (PDG)?
The etiology of diffuse proliferative glomerulonephritis stems from the type and location of deposits seen on renal biopsy; the most commonly associated disease is systemic lupus erythematosus (SLE). Class IV of lupus nephritis shows a diffuse pattern on microscopic examination.
Is diffuse proliferative glomerulonephritis the worst outcome in childhood-onset Lupus nephritis?
“Diffuse proliferative glomerulonephritis does not determine the worst outcome in childhood-onset lupus nephritis: a 23-year experience in a single centre”. Nephrology Dialysis Transplantation. 24 (9): 2729–2734. doi: 10.1093/ndt/gfp173.
Why does infection‐associated proliferative glomerulonephritis require hospitalization?
This is probably due to the fact that the typology of infection‐associated proliferative glomerulonephritis requiring hospitalization has changed over the years in developed countries, with the typical post‐streptococcal‐glomerulonephritis becoming rarer, while the number of cases with severe underlying diseases is progressively increasing.
What is global glomerulonephritis (GL)?
Glomerulonephritis is a term used to describe varying degrees of glomerular injury associated with an activated inflammatory process.