What is an eccrine poroma?
Eccrine poroma is a benign tumor which arises from the intraepidermal portion of the eccrine sweat glands. It usually occurs as a solitary lesion in the extremity, with the foot and sole as a common site. It may present as a foot mass, ulcerative lesion, bleeding lesion, or suspected melanoma.
How is eccrine poroma treated?
Excision is typically the treatment of choice, but cryosurgery has also been used successfully [9]. Jo et al. [10] reported a case of imiquimod 5% cream to treat a poroma, resulting in clearance within 4 weeks.
What causes porocarcinoma?
What is the Cause of the Disease? The exact etiology of porocarcinoma is unknown, but like the benign poroma, it is known to arise from the acrosyringium. It is believed to either arise de novo or by malignant degeneration of a longstanding poroma.
How is porocarcinoma treated?
Porocarcinoma is an aggressive skin cancer. Surgery is the main modality of treatment.
Is eccrine poroma cancerous?
Eccrine porocarcinoma is a rare malignant cutaneous tumor with high rates of extracutaneous spread, and its diagnosis and management can be quite challenging.
What is dermal duct tumor?
Abstract. Dermal duct tumor is a rare, benign tumor. Clinically, dermal duct tumor presents as a firm papule, plaque or nodule, particularly on the lower limbs or head and neck region. Dermal duct tumor is been classified as poroma.
What is metastatic Porocarcinoma?
Abstract. Eccrine porocarcinoma (EPC) is a rare tumor. It develops from the intraepidermal ductal portion of the eccrine sweat gland. Metastatic disease is rare. We report a new case of metastatic eccrine porocarcinoma with a successful management and a good response to docetaxel.
Is a malignant tumor cancerous?
Malignant tumors are cancerous (ie, they invade other sites). They spread to distant sites via the bloodstream or the lymphatic system. This spread is called metastasis. Metastasis can occur anywhere in the body and most commonly is found in the liver, lungs, brain, and bone.
What is the main difference between malignant tumors and benign tumors?
A benign tumor has distinct, smooth, regular borders. A malignant tumor has irregular borders and grows faster than a benign tumor. A malignant tumor can also spread to other parts of your body. A benign tumor can become quite large, but it will not invade nearby tissue or spread to other parts of your body.
What does it mean when something is malignant?
Listen to pronunciation. (muh-LIG-nunt) A term used to describe cancer. Malignant cells grow in an uncontrolled way and can invade nearby tissues and spread to other parts of the body through the blood and lymph system.
Is there such a thing as a malignant eccrine poroma?
There is a malignant eccrine poroma (also known as porocarcinoma), which is a rare tumour. An eccrine poroma typically presents as a solitary dome-shaped papule, plaque or nodule. It can be skin-coloured, pink, red, white or blue, with a smooth, verrucous or ulcerated surface (Ferrari et al 2009 ).
What are eccrine poromas and how can they be treated?
Eccrine poromas and malignant eccrine poromas may also be mistaken for squamous cell carcinoma, carcinoma in situ and amelanotic melanoma (see all above) ( Sawaya & Khachemoune 2014 ). Eccrine poromas can be treated by excision, shave and diathermy, cryotherapy and CO2 laser ( Deckelbaum et al 2014, Sawaya & Khachemoune 2014 ).
Is there a strict classification of malignant eccrine sweat gland tumors?
These cases were compared with previously reported cases of malignant eccrine poroma that had metastasised, and it is suggested that a strict classification of malignant eccrine sweat gland tumours should be made. Full text Full text is available as a scanned copy of the original print version.
Does cytokeratin help in the differentiation of apocrine and eccrine poromas?
Cytokeratin expression has not assisted in the differentiation of apocrine and eccrine poromas.822 Cylindromas are usually found as small solitary lesions on the head and neck. There is a strong predilection for middle-aged and elderly females.