What is cinacalcet used for?
Cinacalcet is used to treat hyperparathyroidism in patients with chronic kidney disease who are on dialysis. Hyperparathyroidism is a condition that is caused when the parathyroid glands located in the neck make too much parathyroid hormone (PTH).
What are the side effects of taking cinacalcet?
Cinacalcet may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- upset stomach.
- vomiting.
- diarrhea.
- dizziness.
- weakness.
- chest pain.
Is cinacalcet a calcium blocker?
Clinical studies have proved cinacalcet to be effective in reducing calcium and PTH levels in primary hyperparathyroidism and in reducing PTH, calcium and phosphate in patients with secondary hyperparathyroidism owing to chronic renal failure, with a relatively safe profile, the only reported adverse events being …
Why is cinacalcet used in dialysis patients?
In initial acute studies in chronic hemodialysis patients, the calcimimetic cinacalcet was shown to reduce plasma intact parathyroid hormone within hours, followed by a rapid, profound decrease in plasma calcium and a minor decrease in plasma phosphorus.
Does cinacalcet cause high blood pressure?
This medicine may cause an increase or decrease in your blood pressure. Check your blood pressure as directed. Ask your doctor or health care professional what your blood pressure should be and when you should contact him or her. This medicine alters the calcium level in your blood.
Does cinacalcet lower blood pressure?
In adjusted models, at 20 weeks cinacalcet resulted in a 2.2 mm Hg larger average decrease in systolic blood pressure (P=0.002) and a 1.3 mm Hg larger average decrease in diastolic blood pressure (P=0.002) compared with placebo.
Is it safe to take cinacalcet?
Cinacalcet can cause low calcium blood levels. Your doctor will check your calcium blood levels while you are taking this medication. Tell your doctor right away if you have any of the following symptoms of low calcium levels: numb/tingling skin, severe muscle spasms, seizures, fast/irregular/pounding heartbeat.
Does cinacalcet raise blood pressure?
How quickly does cinacalcet work?
Clinical studies have shown that PTH response to cinacalcet is rapid, with nadir PTH concentration occurring approximately 3 hours after dosing; PTH concentrations remain suppressed at 24 hours as compared with baseline [12].
Does cinacalcet make you tired?
A concise overview of the drug for the patient or caregiver from First DataBank. SIDE EFFECTS: Nausea, vomiting, or unusual tiredness may occur.
Can cinacalcet cause high blood pressure?