What hemolysis is oxygen-labile?
Streptolysins are two hemolytic exotoxins from Streptococcus. Types include streptolysin O (SLO; slo), which is oxygen-labile, and streptolysin S (SLS; sagA), which is oxygen-stable.
What does it mean to be oxygen-labile?
An oxygen-labile, immunogenic hemolysin produced by or derived from some strains of streptococci. Supplement. A streptolysin is a type of hemolysin (hemolytic exotoxin, in particular) produced by or derived from some strains of streptococci.
Is Streptolysin O oxygen-labile?
Streptolysin O (SLO) is a well-characterized oxygen-labile prototype of a cholesterol-binding bacterial exotoxin.
What are SLO and ASO?
Abstract. Streptolysin O (SLO) is a toxic immunogenic protein produced by Streptococcus pyogenes (S. pyogenes). The latex agglutination photometric immunoassay with latex coated by SLO (latex agglutination method) has been most widely used for determination of antibody to SLO (ASO).
What do streptolysin O and S do?
Streptolysin S is responsible for the β-haemolysis around colonies on blood agar plates. It can also induce the release of lysosomal contents with subsequent cell death after engulfment by phagocytes.
What does Alpha hemolysis indicate?
Alpha hemolysis is a greenish discoloration that surrounds a bacterial colony growing on the agar. This type of hemolysis represents a partial decomposition of the hemoglobin of the red blood cells.
What does labile mean in biology?
Medical Definition of labile : readily or frequently changing: as. a : readily or continually undergoing chemical, physical, or biological change or breakdown a labile antigen.
Which streptolysin is oxygen sensitive?
Tetanolysin is an oxygen-sensitive hemolysin related to streptolysin and the θ-toxin of Clostridium perfringens. It may play a part in establishing infection at the site of inoculation, but it has no other known role in pathogenesis of the disease.
What is the relationship between hemolysis and streptolysin?
What group of Streptococcus produces streptolysin O?
group A streptococcus
Bacteria called group A streptococcus (GAS) causes common infections such as strep throat and skin infections. GAS produces a toxic enzyme known as streptolysin O.
How do you distinguish between alpha and beta hemolysis?
In alpha hemolysis, red blood cells break down completely. In beta hemolysis, red blood cells break down partially. Alpha Hemolysis indicates the production of clear zones around the bacterial colonies on blood agar plates. Beta Hemolysis indicates greenish colour around the bacterial growth in blood agar plates.